Name: Robin de Nijs (e-mail)
Title: MSc, PDEng, PhD
• Specialist Medical Physicist (SMP) at Rigshospitalet, Copenhagen University Hospital, Dep. of Clinical Physiology, Nuclear Medicine and PET
• Member of the Danish Society for Medical Physics
- Area of interest
- Activities
- Education
- List of publications
- CV
As a medical physicist in nuclear medicine I am interested in optimizing image quality, quantitative imaging and correction methods for scatter and attenuation.
Validation of the vendor's software for calculations and reconstruction is an important and necessary occupation.
I have developed dosimetry calculations based on quantitative SPECT for radionuclide therapy with 177Lu-Dotatate.
As a medical physicist I perform the annual NEMA QC-measurements on the SPECT- and gamma-cameras. For the independent analysis a QC-software suite is being developed in cooperation with two other hospitals. Our intention is to add PET NEMA QC-measurements to this software.
Simultaneous PET and MR-spectroscopy including motion compensation on the PET-MR have my interest.
Member of the Danish Society for Medical Physics
Danish Society for Medical Physics is a scientific community related to the application of radiation in the diagnostic and therapeutic areas in health care. The society represents the group of hospital physicists in the hospital departments utilising ionising radiation, i.e. the areas of radiation oncology, x-ray diagnostics and nuclear medicine.
Education
2005 - 2010 PhD in medical physics and data analysis. Technical University of Denmark, Danish Research Centre for Magnetic Resonance, Copenhagen University Hospital, Hvidovre, Neurobiology Research Unit, Rigshospitalet, Copenhagen University Hospital
1999 - 2002 Specialist Medical Physicist (SMP), general medical physics, medical imaging techniques, European Federation of Organisations in Medical Physics (EFOMP), Dutch Society for Medical Physics (NVKF)
1999 - 2001 Professional Doctorate in Engineering (PDEng) in medical physics and technological design, Eindhoven University of Technology, the Netherlands
1996 - 1997 Certified teacher (MEd) in physics, Eindhoven University of Technology, Het Augustinianum, Eindhoven, Noerre G, Husum, Denmark University of Technology, the Netherlands
1990 - 1996 Master of Science (MSc) in applied physics, University of Technology TU/e, Eindhoven main subjects: fluid dynamics and nuclear physics
Jensen P, Feng L, Law I, Svarer C, Knudsen GM, Mikkelsen J, de Nijs R, Larsen VA, Dyssegaard A, Thomsen G, Fisher W, Pinborg LH. TSPO imaging in GBM overlaps with subsequent tumor expansion: A direct comparison between [123I]CLINDE-SPECT, [18F]FET-PET and MRI. Neurol Neurosurg Psychiatry 2014;submitted 11/2014.
Willowson KP, Bailey DL, Tapner M, Holm S, Mortensen J,de Nijs R, QUEST Investigator team. A multi-centre comparison of quantitative 90-Y PET/CT for dosimetric purposes after radioembolisation. EJNMMI Research 2014; submitted 9/2014
Feng L, Svarer C, Thomsen G, de Nijs R, Larsen VA, Jensen P, Adamsen D, Dyssegaard A, Fischer W, Meden P, Krieger D, Møller K, Knudsen GM, Pinborg LH.. In Vivo Quantification of Cerebral Translocator Protein Binding in Humans Using 6-Chloro-2-(4?-123I-Iodophenyl)- 3-(N,N-Diethyl)-Imidazo[1,2-a]Pyridine-3-Acetamide SPECT. J Nucl Med. 2014;55(12):1966-72.
de Nijs R, Jensen BN, Mortensen J. Missing head and color banding in low count SPECT reconstructions. EJNMMI Physics. 2014;1:10 (5pp)
de Nijs R, Lagerburg V, Klausen TL, Holm S. Improving quantitative dosimetry in 177-Lu-DOTATATE SPECT by energy window based scatter corrections. Nucl Med Commun. 2014;35(5):522-33.
de Nijs R, Klausen TL. On the expected difference between mean and median. EJASA Electron J App Stat Anal. 2013;6(1):110-7.
Balyasnikova S, Löfgren J, de Nijs R, Zamogilnaya Y, Højgaard L, Fischer BM. PET/MR in oncology: an introduction with focus on MR and future perspectives for hybrid imaging. Am J Nucl Med Mol Imaging. 2012;2(4):458-474.
Lagerburg V, de Nijs R, Holm S, Svarer C. A comparison of different energy window subtraction methods to correct for scatter and downscatter in I-123 SPECT imaging. Nucl Med Commun. 2012 Jul;33(7):708-18.
Dickson JC, Tossici-Bolt L, Sera T, de Nijs R, Booij J, Bagnara MC, Seese A, Koulibaly PM, Akdemir UO, Jonsson C, Koole M, Raith M, Lonsdale MN, George J, Zito F, Tatsch K. Proposal for the standardisation of multi-centre trials in nuclear medicine imaging: prerequisites for a European (123)I-FP-CIT SPECT database. Eur J Nucl Med Mol Imaging. 2012;39(1):188-97.
Jensen PS, Ziebell M, Skouboe G, Khalid U, de Nijs R, Thomsen G, Knudsen GM, Svarer C.Validation of a Method for Accurate and Highly Reproducible Quantification of Brain Dopamine Transporter SPECT Studies. J Nucl Med Technol. 2011;39(4):271-8.
Vickery A, Jørgensen T, de Nijs R. NEMA NU-1 2007 based and independent Quality Control software for gamma cameras and SPECT. J Phys: Conf Ser. 2011;317:012023. (5pp)
Tossici-Bolt L, Dickson JC, Sera T, de Nijs R, Bagnara MC, Jonsson C, Scheepers E, Zito F, Seese A, Koulibaly PM, Kapucu OL, Koole M, Raith M, George J, Lonsdale MN, Münzing W, Tatsch K, Varrone A. Calibration of gamma camera systems for a multicentre European ¹²³I-FP-CIT SPECT normal database. Eur J Nucl Med Mol Imaging. 2011;38(8):1529-40.
de Nijs R, Holm S, Thomsen G, Ziebell M, Svarer C. Experimental determination of the weighting factor for the energy window subtraction-based downscatter correction for I-123 in brain SPECT studies. J Med Phys. 2010;35(4):215-22.
Ziebell M, Pinborg LH, Thomsen G, de Nijs R, Svarer C, Wagner A, Knudsen GM. MRI-guided region-of-interest delineation is comparable to manual delineation in dopamine transporter SPECT quantification in patients: a reproducibility study. J Nucl Med Technol. 2010;38(2):61-8.
de Nijs R, Miranda MJ, Hansen LK, Hanson LG. Motion correction of single-voxel spectroscopy by independent component analysis applied to spectra from nonanesthetized pediatric subjects. Magn Reson Med. 2009;62(5):1147-54.
Sardanelli F, Fausto A, Di Leo G, de Nijs R, Vorbuchner M, Podo F. In vivo proton MR spectroscopy of the breast using the total choline peak integral as a marker of malignancy. AJR Am J Roentgenol. 2009;192(6):1608-17.
Thomsen G, de Nijs R, Hogh-Rasmussen E, Frokjaer V, Svarer C, Knudsen GM. Required time delay from 99mTc-HMPAO injection to SPECT data acquisition: healthy subjects and patients with rCBF pattern. Eur J Nucl Med Mol Imaging. 2008;35(12):2212-9.
Frokjaer VG, Pinborg LH, Madsen J, de Nijs R, Svarer C, Wagner A, Knudsen GM. Evaluation of the Serotonin Transporter Ligand 123I-ADAM for SPECT Studies on Humans. J Nucl Med. 2008;49(2):247-54. Erratum in: J Nucl Med. 2010;51(3):470.
Ziebell M, Thomsen G, Knudsen GM, de Nijs R, Svarer C, Wagner A, Pinborg LH. Reproducibility of [123I]PE2I binding to dopamine transporters with SPECT. Eur J Nucl Med Mol Imaging. 2007;34(1):101-9.
Pinborg LH, Ziebell M, Frøkjaer VG, de Nijs R, Svarer C, Haugbøl S, Yndgaard S, Knudsen GM. Quantification of 123I-PE2I binding to dopamine transporter with SPECT after bolus and bolus/infusion. J Nucl Med. 2005;46(7):1119-27.
The Curriculum Vitae can be downloaded here as a *PDF file: Robin_De_Nijs_CV.pdf